++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++ + SHELXTL XLMP CRYSTAL STRUCTURE REFINEMENT - MULTI-CPU VERSION + + Copyright(c) Bruker AXS Inc. 1993-2018 Version 2018/3 + + neal054 started at 12:14:29 on 19-Oct-2021 + ++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++ Command line parameters: neal054 -a50000 -b3000 -c624 -g0 -m0 -t12 -a sets the approximate maximum number of atoms including hydrogens. -b sets the maximum number of full-matrix parameters (not used by CGLS). For example -b9000 allows refinement of 1000 anisotropic atoms or 3000 with BLOC 1. For a 32-bit version, -b times the square root of the number of threads should not exceed about 65500. -c sets the reflection buffer size. This depends on the CPU cache size but will rarely need changing. -g sets the number of reflection groups used for calculating R_complete, This must be greater than 1 but not greater than the total number of reflections for refinement. -m sets the current reflection group number. This may not be less than 1 nor greater than the number set by -g. These command line flags override other ways of defining free-R reflections. The -m value is also used as a seed for the WIGL pseudo-random shifts. -t sets the number of threads, otherwise it is set to the apparent number of CPUs. For optimal performance on hyperthreading systems, -t should be set to a little more than half the number of CPUs; e.g. -t4 or -t5 for an Intel i7 processor. Running 12 threads on 12 processors TITL neal054 in P2(1) CELL 1.54178 6.2572 11.763 13.0387 90 96.6572 90 ZERR 2 0.0005 0.0009 0.001 0 0.0027 0 LATT -1 SYMM -X,0.5+Y,-Z SFAC C H N O I UNIT 34 46 4 8 2 V = 953.22 F(000) = 448.0 Mu = 13.39 mm-1 Cell Wt = 892.55 Rho = 1.555 L.S. 20 PLAN 30 SIZE 0.028 0.099 0.172 TEMP -173.15 CONF BOND $H LIST 6 MORE -1 fmap 2 ACTA WGHT 0.0522 1.0934 FVAR 0.17752 REM REM REM I1 5 1.07140 0.20810 -0.02957 11.00000 0.05034 0.04733 0.03001 = -0.01120 -0.00010 0.00966 O1 4 -0.00416 0.58955 0.43818 11.00000 0.02615 0.02643 0.05111 = -0.00360 0.00350 -0.00321 O2 4 0.44225 0.59324 0.60549 11.00000 0.03306 0.01865 0.02023 = -0.00324 0.00448 0.00713 O3 4 0.59559 0.42702 0.56160 11.00000 0.02790 0.01522 0.02685 = -0.00040 0.00758 0.00440 O4 4 0.48098 0.55008 0.16942 11.00000 0.03379 0.04194 0.02025 = -0.00204 0.00215 0.00231 N1 3 0.07941 0.77008 0.48851 11.00000 0.02037 0.01767 0.03777 = -0.00070 0.00597 -0.00088 H1 2 0.14899 0.81540 0.48779 11.00000 0.01464 N2 3 0.44968 0.55230 0.44097 11.00000 0.02303 0.01584 0.02195 = -0.00319 0.00440 0.00191 C1 1 -0.12451 0.79573 0.52624 11.00000 0.02689 0.02825 0.06497 = 0.00209 0.01218 0.00223 AFIX 137 H1a 2 -0.11625 0.87057 0.55948 11.00000 -1.50000 H1b 2 -0.15577 0.73783 0.57645 11.00000 -1.50000 H1c 2 -0.23917 0.79611 0.46827 11.00000 -1.50000 AFIX 0 C2 1 0.12200 0.66948 0.44870 11.00000 0.01709 0.01613 0.03226 = 0.00477 -0.00122 -0.00300 C3 1 0.34649 0.66167 0.41317 11.00000 0.01960 0.01763 0.02414 = 0.00029 -0.00052 0.00061 H3 2 0.43139 0.72823 0.44095 11.00000 0.01146 C4 1 0.33876 0.66310 0.29555 11.00000 0.03518 0.02150 0.02660 = 0.00410 -0.00082 -0.00091 H4a 2 0.34138 0.73362 0.26999 11.00000 0.01525 H4b 2 0.22022 0.62254 0.27716 11.00000 0.02311 C5 1 0.52327 0.58834 0.27346 11.00000 0.02890 0.03126 0.01779 = 0.00122 0.00318 -0.00641 H5 2 0.65483 0.63729 0.27984 11.00000 0.03689 C6 1 0.52440 0.49430 0.35348 11.00000 0.02662 0.02058 0.02072 = -0.00242 0.00810 -0.00450 H6a 2 0.40892 0.43485 0.32569 11.00000 0.02876 H6b 2 0.67065 0.46713 0.36813 11.00000 0.05313 C7 1 0.50351 0.51670 0.53849 11.00000 0.01839 0.01608 0.02508 = -0.00534 0.00445 -0.00284 C8 1 0.45224 0.56486 0.71663 11.00000 0.04359 0.03136 0.01870 = -0.00372 0.00794 0.00350 C9 1 0.68328 0.54612 0.76294 11.00000 0.04935 0.04202 0.02508 = 0.00113 -0.00509 -0.00114 AFIX 137 H9a 2 0.73742 0.47535 0.73583 11.00000 -1.50000 H9b 2 0.68953 0.54095 0.83824 11.00000 -1.50000 H9c 2 0.77215 0.60994 0.74465 11.00000 -1.50000 AFIX 0 C10 1 0.30825 0.46215 0.72957 11.00000 0.04725 0.04308 0.03533 = 0.00789 0.02378 0.00274 AFIX 137 H10a 2 0.16909 0.47297 0.68786 11.00000 -1.50000 H10b 2 0.28602 0.45428 0.80241 11.00000 -1.50000 H10c 2 0.37728 0.39333 0.70675 11.00000 -1.50000 AFIX 0 C11 1 0.35688 0.67038 0.75908 11.00000 0.08078 0.04280 0.03443 = -0.01016 0.02068 0.01592 AFIX 137 H11a 2 0.44306 0.73673 0.74440 11.00000 -1.50000 H11b 2 0.35678 0.66253 0.83390 11.00000 -1.50000 H11c 2 0.20891 0.68038 0.72649 11.00000 -1.50000 AFIX 0 C12 1 0.54818 0.42475 0.03891 11.00000 0.03959 0.04415 0.02119 = 0.00230 0.00045 -0.00312 H12 2 0.39563 0.43592 0.01953 11.00000 0.07262 C13 1 0.67628 0.34973 -0.00640 11.00000 0.04318 0.04930 0.01689 = -0.00532 0.00047 -0.00156 H13 2 0.62166 0.31263 -0.05751 11.00000 0.02343 C14 1 0.88432 0.32906 0.03821 11.00000 0.04311 0.03080 0.02474 = -0.00346 0.01069 0.00353 C15 1 0.96416 0.38279 0.12965 11.00000 0.02951 0.03200 0.02398 = 0.00094 0.00237 -0.00475 H15 2 1.08980 0.36569 0.16093 11.00000 0.02493 C16 1 0.83246 0.45663 0.17644 11.00000 0.03567 0.03376 0.02207 = -0.00103 0.00714 -0.00808 H16 2 0.87693 0.49653 0.23491 11.00000 0.02863 C17 1 0.62577 0.47845 0.13209 11.00000 0.03201 0.03666 0.02097 = 0.00340 0.00673 -0.00860 HKLF 4 Covalent radii and connectivity table for neal054 in P2(1) C 0.770 H 0.320 N 0.700 O 0.660 I 1.330 I1 - C14 O1 - C2 O2 - C7 C8 O3 - C7 O4 - C17 C5 N1 - C2 C1 N2 - C7 C6 C3 C1 - N1 C2 - O1 N1 C3 C3 - N2 C4 C2 C4 - C5 C3 C5 - O4 C4 C6 C6 - N2 C5 C7 - O3 O2 N2 C8 - O2 C11 C9 C10 C9 - C8 C10 - C8 C11 - C8 C12 - C13 C17 C13 - C12 C14 C14 - C13 C15 I1 C15 - C16 C14 C16 - C17 C15 C17 - O4 C16 C12 Floating origin restraints generated h k l Fo^2 Sigma Why rejected (first 50 of each listed) 0 -1 0 0.27 0.04 systematically absent but >3sig(I) 0 -3 0 0.34 0.10 systematically absent but >3sig(I) 0 -3 0 0.28 0.07 systematically absent but >3sig(I) 0 -3 0 0.28 0.09 systematically absent but >3sig(I) 0 -3 0 0.31 0.07 systematically absent but >3sig(I) 0 -3 0 0.35 0.08 systematically absent but >3sig(I) 0 -3 0 0.22 0.05 systematically absent but >3sig(I) 0 -3 0 0.32 0.06 systematically absent but >3sig(I) 0 -3 0 0.38 0.12 systematically absent but >3sig(I) 46 Systematically absent reflections rejected 18124 Reflections read, of which 46 rejected -7 =< h =< 7, -13 =< k =< 13, -15 =< l =< 15, Max. 2-theta = 127.62 9 Systematic absence violations (I>3sig(I)) before merging 0 Inconsistent equivalents 3118 Unique reflections, of which 0 suppressed R(int) = 0.0562 R(sigma) = 0.0339 Friedel opposites not merged Maximum memory for data reduction = 2805 / 31237 Reflection statistics for all twin components combined (TWST 0 set) Number of data for d > 0.859A (CIF: max) and d > 0.859A (CIF: full) (ignoring systematic absences): Unique reflections found (point group) 3118 3117 Unique reflections possible (point group) 3144 3142 Unique reflections found (Laue group) 1652 1651 Unique reflections possible (Laue group) 1659 1658 Unique Friedel pairs found 1466 1466 Unique Friedel pairs possible 1485 1484 Default effective X-H and X-D distances for T = -173.2C AFIX m = 1 2 3 4 4[N] 3[N] 15[B] 8[O] 9 9[N] 16 d(X-H) = 1.00 0.99 0.98 0.95 0.88 0.91 1.12 0.84 0.95 0.88 0.95 Note that these distances are chosen to give the best fit to the X-ray data and so avoid the introduction of systematic error. The true internuclear distances are longer and do not vary with temperature! The apparent variation with temperature is caused by libration. Least-squares cycle 1 Maximum vector length = 623 Memory required = 56 / 3496 / 395246 wR2 = 0.087275 before cycle 1 for 3118 data and 265 / 265 parameters GooF = S = 1.077; Restrained GooF = 1.077 for 1 restraints Weight = 1 / [ sigma^2(Fo^2) + ( 0.0522 * P )^2 + 1.09 * P ] where P = ( Max ( Fo^2, 0 ) + 2 * Fc^2 ) / 3 N value esd shift/esd parameter 1 0.17752 0.00048 -0.009 OSF Mean shift/esd = 0.002 Maximum = -0.024 for x I1 Max. shift = 0.000 A for H12 Max. dU = 0.000 for H6B Least-squares cycle 2 Maximum vector length = 623 Memory required = 56 / 3496 / 395246 wR2 = 0.087275 before cycle 2 for 3118 data and 265 / 265 parameters GooF = S = 1.077; Restrained GooF = 1.077 for 1 restraints Weight = 1 / [ sigma^2(Fo^2) + ( 0.0522 * P )^2 + 1.09 * P ] where P = ( Max ( Fo^2, 0 ) + 2 * Fc^2 ) / 3 N value esd shift/esd parameter 1 0.17751 0.00048 -0.001 OSF Mean shift/esd = 0.001 Maximum = -0.008 for x I1 Max. shift = 0.000 A for H12 Max. dU = 0.000 for H5 Least-squares cycle 3 Maximum vector length = 623 Memory required = 56 / 3496 / 395246 wR2 = 0.087275 before cycle 3 for 3118 data and 265 / 265 parameters GooF = S = 1.077; Restrained GooF = 1.077 for 1 restraints Weight = 1 / [ sigma^2(Fo^2) + ( 0.0522 * P )^2 + 1.09 * P ] where P = ( Max ( Fo^2, 0 ) + 2 * Fc^2 ) / 3 N value esd shift/esd parameter 1 0.17751 0.00048 0.000 OSF Mean shift/esd = 0.000 Maximum = 0.001 for x H6B Max. shift = 0.000 A for H12 Max. dU = 0.000 for H6B Least-squares cycle 4 Maximum vector length = 623 Memory required = 56 / 3496 / 395246 wR2 = 0.087275 before cycle 4 for 3118 data and 265 / 265 parameters GooF = S = 1.077; Restrained GooF = 1.077 for 1 restraints Weight = 1 / [ sigma^2(Fo^2) + ( 0.0522 * P )^2 + 1.09 * P ] where P = ( Max ( Fo^2, 0 ) + 2 * Fc^2 ) / 3 N value esd shift/esd parameter 1 0.17751 0.00048 0.000 OSF Mean shift/esd = 0.000 Maximum = 0.000 for x H6B Max. shift = 0.000 A for H6B Max. dU = 0.000 for H6B Least-squares cycle 5 Maximum vector length = 623 Memory required = 56 / 3496 / 395246 wR2 = 0.087275 before cycle 5 for 3118 data and 265 / 265 parameters GooF = S = 1.077; Restrained GooF = 1.077 for 1 restraints Weight = 1 / [ sigma^2(Fo^2) + ( 0.0522 * P )^2 + 1.09 * P ] where P = ( Max ( Fo^2, 0 ) + 2 * Fc^2 ) / 3 N value esd shift/esd parameter 1 0.17751 0.00048 0.000 OSF Mean shift/esd = 0.000 Maximum = 0.000 for x H6B Max. shift = 0.000 A for H6B Max. dU = 0.000 for H6B Least-squares cycle 6 Maximum vector length = 623 Memory required = 56 / 3496 / 395246 wR2 = 0.087275 before cycle 6 for 3118 data and 265 / 265 parameters GooF = S = 1.077; Restrained GooF = 1.077 for 1 restraints Weight = 1 / [ sigma^2(Fo^2) + ( 0.0522 * P )^2 + 1.09 * P ] where P = ( Max ( Fo^2, 0 ) + 2 * Fc^2 ) / 3 N value esd shift/esd parameter 1 0.17751 0.00048 0.000 OSF Mean shift/esd = 0.000 Maximum = 0.000 for x H6B Max. shift = 0.000 A for H6B Max. dU = 0.000 for H6B Least-squares cycle 7 Maximum vector length = 623 Memory required = 56 / 3496 / 395246 wR2 = 0.087275 before cycle 7 for 3118 data and 265 / 265 parameters GooF = S = 1.077; Restrained GooF = 1.077 for 1 restraints Weight = 1 / [ sigma^2(Fo^2) + ( 0.0522 * P )^2 + 1.09 * P ] where P = ( Max ( Fo^2, 0 ) + 2 * Fc^2 ) / 3 N value esd shift/esd parameter 1 0.17751 0.00048 0.000 OSF Mean shift/esd = 0.000 Maximum = 0.000 for x H6B Max. shift = 0.000 A for H6B Max. dU = 0.000 for H6B Least-squares cycle 8 Maximum vector length = 623 Memory required = 56 / 3496 / 395246 wR2 = 0.087275 before cycle 8 for 3118 data and 265 / 265 parameters GooF = S = 1.077; Restrained GooF = 1.077 for 1 restraints Weight = 1 / [ sigma^2(Fo^2) + ( 0.0522 * P )^2 + 1.09 * P ] where P = ( Max ( Fo^2, 0 ) + 2 * Fc^2 ) / 3 N value esd shift/esd parameter 1 0.17751 0.00048 0.000 OSF Mean shift/esd = 0.000 Maximum = 0.000 for x H6B Max. shift = 0.000 A for H6B Max. dU = 0.000 for H6B Least-squares cycle 9 Maximum vector length = 623 Memory required = 56 / 3496 / 395246 wR2 = 0.087275 before cycle 9 for 3118 data and 265 / 265 parameters GooF = S = 1.077; Restrained GooF = 1.077 for 1 restraints Weight = 1 / [ sigma^2(Fo^2) + ( 0.0522 * P )^2 + 1.09 * P ] where P = ( Max ( Fo^2, 0 ) + 2 * Fc^2 ) / 3 N value esd shift/esd parameter 1 0.17751 0.00048 0.000 OSF Mean shift/esd = 0.000 Maximum = 0.000 for x H6B Max. shift = 0.000 A for H6B Max. dU = 0.000 for H6B Least-squares cycle 10 Maximum vector length = 623 Memory required = 56 / 3496 / 395246 wR2 = 0.087275 before cycle 10 for 3118 data and 265 / 265 parameters GooF = S = 1.077; Restrained GooF = 1.077 for 1 restraints Weight = 1 / [ sigma^2(Fo^2) + ( 0.0522 * P )^2 + 1.09 * P ] where P = ( Max ( Fo^2, 0 ) + 2 * Fc^2 ) / 3 N value esd shift/esd parameter 1 0.17751 0.00048 0.000 OSF Mean shift/esd = 0.000 Maximum = 0.000 for x H6B Max. shift = 0.000 A for H6B Max. dU = 0.000 for H6B Least-squares cycle 11 Maximum vector length = 623 Memory required = 56 / 3496 / 395246 wR2 = 0.087275 before cycle 11 for 3118 data and 265 / 265 parameters GooF = S = 1.077; Restrained GooF = 1.077 for 1 restraints Weight = 1 / [ sigma^2(Fo^2) + ( 0.0522 * P )^2 + 1.09 * P ] where P = ( Max ( Fo^2, 0 ) + 2 * Fc^2 ) / 3 N value esd shift/esd parameter 1 0.17751 0.00048 0.000 OSF Mean shift/esd = 0.000 Maximum = 0.000 for x H6B Max. shift = 0.000 A for H6B Max. dU = 0.000 for H6B Least-squares cycle 12 Maximum vector length = 623 Memory required = 56 / 3496 / 395246 wR2 = 0.087275 before cycle 12 for 3118 data and 265 / 265 parameters GooF = S = 1.077; Restrained GooF = 1.077 for 1 restraints Weight = 1 / [ sigma^2(Fo^2) + ( 0.0522 * P )^2 + 1.09 * P ] where P = ( Max ( Fo^2, 0 ) + 2 * Fc^2 ) / 3 N value esd shift/esd parameter 1 0.17751 0.00048 0.000 OSF Mean shift/esd = 0.000 Maximum = 0.000 for x H6B Max. shift = 0.000 A for H6B Max. dU = 0.000 for H6B Least-squares cycle 13 Maximum vector length = 623 Memory required = 56 / 3496 / 395246 wR2 = 0.087275 before cycle 13 for 3118 data and 265 / 265 parameters GooF = S = 1.077; Restrained GooF = 1.077 for 1 restraints Weight = 1 / [ sigma^2(Fo^2) + ( 0.0522 * P )^2 + 1.09 * P ] where P = ( Max ( Fo^2, 0 ) + 2 * Fc^2 ) / 3 N value esd shift/esd parameter 1 0.17751 0.00048 0.000 OSF Mean shift/esd = 0.000 Maximum = 0.000 for x H6B Max. shift = 0.000 A for H6B Max. dU = 0.000 for H6B Least-squares cycle 14 Maximum vector length = 623 Memory required = 56 / 3496 / 395246 wR2 = 0.087275 before cycle 14 for 3118 data and 265 / 265 parameters GooF = S = 1.077; Restrained GooF = 1.077 for 1 restraints Weight = 1 / [ sigma^2(Fo^2) + ( 0.0522 * P )^2 + 1.09 * P ] where P = ( Max ( Fo^2, 0 ) + 2 * Fc^2 ) / 3 N value esd shift/esd parameter 1 0.17751 0.00048 0.000 OSF Mean shift/esd = 0.000 Maximum = 0.000 for x H6B Max. shift = 0.000 A for H6B Max. dU = 0.000 for H6B Least-squares cycle 15 Maximum vector length = 623 Memory required = 56 / 3496 / 395246 wR2 = 0.087275 before cycle 15 for 3118 data and 265 / 265 parameters GooF = S = 1.077; Restrained GooF = 1.077 for 1 restraints Weight = 1 / [ sigma^2(Fo^2) + ( 0.0522 * P )^2 + 1.09 * P ] where P = ( Max ( Fo^2, 0 ) + 2 * Fc^2 ) / 3 N value esd shift/esd parameter 1 0.17751 0.00048 0.000 OSF Mean shift/esd = 0.000 Maximum = 0.000 for x H6B Max. shift = 0.000 A for H6B Max. dU = 0.000 for H6B Least-squares cycle 16 Maximum vector length = 623 Memory required = 56 / 3496 / 395246 wR2 = 0.087275 before cycle 16 for 3118 data and 265 / 265 parameters GooF = S = 1.077; Restrained GooF = 1.077 for 1 restraints Weight = 1 / [ sigma^2(Fo^2) + ( 0.0522 * P )^2 + 1.09 * P ] where P = ( Max ( Fo^2, 0 ) + 2 * Fc^2 ) / 3 N value esd shift/esd parameter 1 0.17751 0.00048 0.000 OSF Mean shift/esd = 0.000 Maximum = 0.000 for x H6B Max. shift = 0.000 A for H6B Max. dU = 0.000 for H6B Least-squares cycle 17 Maximum vector length = 623 Memory required = 56 / 3496 / 395246 wR2 = 0.087275 before cycle 17 for 3118 data and 265 / 265 parameters GooF = S = 1.077; Restrained GooF = 1.077 for 1 restraints Weight = 1 / [ sigma^2(Fo^2) + ( 0.0522 * P )^2 + 1.09 * P ] where P = ( Max ( Fo^2, 0 ) + 2 * Fc^2 ) / 3 N value esd shift/esd parameter 1 0.17751 0.00048 0.000 OSF Mean shift/esd = 0.000 Maximum = 0.000 for x H6B Max. shift = 0.000 A for H6B Max. dU = 0.000 for H6B Least-squares cycle 18 Maximum vector length = 623 Memory required = 56 / 3496 / 395246 wR2 = 0.087275 before cycle 18 for 3118 data and 265 / 265 parameters GooF = S = 1.077; Restrained GooF = 1.077 for 1 restraints Weight = 1 / [ sigma^2(Fo^2) + ( 0.0522 * P )^2 + 1.09 * P ] where P = ( Max ( Fo^2, 0 ) + 2 * Fc^2 ) / 3 N value esd shift/esd parameter 1 0.17751 0.00048 0.000 OSF Mean shift/esd = 0.000 Maximum = 0.000 for x H6B Max. shift = 0.000 A for H6B Max. dU = 0.000 for H6B Least-squares cycle 19 Maximum vector length = 623 Memory required = 56 / 3496 / 395246 wR2 = 0.087275 before cycle 19 for 3118 data and 265 / 265 parameters GooF = S = 1.077; Restrained GooF = 1.077 for 1 restraints Weight = 1 / [ sigma^2(Fo^2) + ( 0.0522 * P )^2 + 1.09 * P ] where P = ( Max ( Fo^2, 0 ) + 2 * Fc^2 ) / 3 N value esd shift/esd parameter 1 0.17751 0.00048 0.000 OSF Mean shift/esd = 0.000 Maximum = 0.000 for x H6B Max. shift = 0.000 A for H6B Max. dU = 0.000 for H6B Least-squares cycle 20 Maximum vector length = 623 Memory required = 56 / 3496 / 395246 wR2 = 0.087275 before cycle 20 for 3118 data and 265 / 265 parameters GooF = S = 1.077; Restrained GooF = 1.077 for 1 restraints Weight = 1 / [ sigma^2(Fo^2) + ( 0.0522 * P )^2 + 1.09 * P ] where P = ( Max ( Fo^2, 0 ) + 2 * Fc^2 ) / 3 N value esd shift/esd parameter 1 0.17751 0.00048 0.000 OSF Mean shift/esd = 0.000 Maximum = 0.000 for x H6B Max. shift = 0.000 A for H6B Max. dU = 0.000 for H6B Largest correlation matrix elements 0.600 U33 I1 / OSF 0.585 U22 I1 / OSF 0.591 U11 I1 / OSF 0.546 U11 H1 / U12 N1 Idealized hydrogen atom generation before cycle 21 Name x y z AFIX d(X-H) shift Bonded to Conformation determined by H1A -0.1163 0.8706 0.5595 137 0.980 0.000 C1 N1 H1A H1B -0.1558 0.7378 0.5764 137 0.980 0.000 C1 N1 H1A H1C -0.2392 0.7961 0.4683 137 0.980 0.000 C1 N1 H1A H9A 0.7374 0.4753 0.7358 137 0.980 0.000 C9 C8 H9A H9B 0.6895 0.5409 0.8382 137 0.980 0.000 C9 C8 H9A H9C 0.7722 0.6099 0.7447 137 0.980 0.000 C9 C8 H9A H10A 0.1691 0.4730 0.6879 137 0.980 0.000 C10 C8 H10A H10B 0.2860 0.4543 0.8024 137 0.980 0.000 C10 C8 H10A H10C 0.3773 0.3933 0.7067 137 0.980 0.000 C10 C8 H10A H11A 0.4431 0.7367 0.7444 137 0.980 0.000 C11 C8 H11A H11B 0.3568 0.6625 0.8339 137 0.980 0.000 C11 C8 H11A H11C 0.2089 0.6804 0.7265 137 0.980 0.000 C11 C8 H11A neal054 in P2(1) ATOM x y z sof U11 U22 U33 U23 U13 U12 Ueq I1 1.07140 0.20810 -0.02957 1.00000 0.05034 0.04733 0.03001 -0.01120 -0.00010 0.00966 0.04293 0.00072 0.00007 0.00004 0.00003 0.00000 0.00029 0.00029 0.00026 0.00023 0.00017 0.00026 0.00019 O1 -0.00416 0.58955 0.43818 1.00000 0.02615 0.02643 0.05112 -0.00360 0.00350 -0.00321 0.03464 0.00946 0.00078 0.00042 0.00043 0.00000 0.00237 0.00247 0.00318 0.00228 0.00230 0.00202 0.00112 O2 0.44225 0.59325 0.60549 1.00000 0.03307 0.01865 0.02023 -0.00324 0.00448 0.00713 0.02387 0.00825 0.00071 0.00036 0.00034 0.00000 0.00240 0.00207 0.00223 0.00172 0.00181 0.00180 0.00093 O3 0.59559 0.42702 0.56160 1.00000 0.02790 0.01521 0.02685 -0.00040 0.00758 0.00440 0.02298 0.00839 0.00072 0.00036 0.00034 0.00000 0.00230 0.00214 0.00244 0.00173 0.00182 0.00177 0.00093 O4 0.48098 0.55008 0.16942 1.00000 0.03379 0.04193 0.02025 -0.00204 0.00215 0.00231 0.03207 0.00889 0.00080 0.00043 0.00037 0.00000 0.00253 0.00288 0.00236 0.00200 0.00192 0.00210 0.00109 N1 0.07941 0.77008 0.48851 1.00000 0.02037 0.01768 0.03776 -0.00070 0.00597 -0.00088 0.02507 0.01314 0.00096 0.00061 0.00052 0.00000 0.00317 0.00347 0.00353 0.00265 0.00256 0.00240 0.00135 H1 0.14901 0.81541 0.48780 1.00000 0.01466 0.15186 0.01270 0.00737 0.00572 0.00000 0.02019 N2 0.44968 0.55230 0.44097 1.00000 0.02303 0.01584 0.02195 -0.00319 0.00440 0.00191 0.02013 0.00937 0.00083 0.00042 0.00041 0.00000 0.00260 0.00254 0.00275 0.00195 0.00209 0.00202 0.00108 C1 -0.12451 0.79573 0.52624 1.00000 0.02689 0.02826 0.06497 0.00209 0.01219 0.00222 0.03950 0.01588 0.00125 0.00068 0.00071 0.00000 0.00348 0.00361 0.00569 0.00334 0.00346 0.00305 0.00185 H1A -0.11626 0.87058 0.55948 1.00000 0.05925 0.00000 0.00000 H1B -0.15577 0.73783 0.57645 1.00000 0.05925 0.00000 0.00000 H1C -0.23918 0.79611 0.46827 1.00000 0.05925 0.00000 0.00000 C2 0.12200 0.66949 0.44870 1.00000 0.01709 0.01613 0.03226 0.00477 -0.00122 -0.00300 0.02215 0.01174 0.00107 0.00052 0.00058 0.00000 0.00274 0.00312 0.00340 0.00250 0.00270 0.00230 0.00134 C3 0.34650 0.66167 0.41317 1.00000 0.01960 0.01763 0.02414 0.00029 -0.00051 0.00061 0.02070 0.01150 0.00098 0.00052 0.00050 0.00000 0.00294 0.00274 0.00341 0.00238 0.00251 0.00241 0.00127 H3 0.43140 0.72822 0.44095 1.00000 0.01148 0.12298 0.00939 0.00605 0.00457 0.00000 0.01459 C4 0.33876 0.66310 0.29555 1.00000 0.03517 0.02150 0.02660 0.00410 -0.00082 -0.00091 0.02810 0.01495 0.00130 0.00067 0.00058 0.00000 0.00376 0.00323 0.00388 0.00277 0.00300 0.00282 0.00148 H4A 0.34138 0.73364 0.26999 1.00000 0.01525 0.12711 0.01070 0.00709 0.00531 0.00000 0.01679 H4B 0.22020 0.62254 0.27715 1.00000 0.02311 0.15232 0.01278 0.00663 0.00582 0.00000 0.01780 C5 0.52327 0.58834 0.27345 1.00000 0.02890 0.03125 0.01779 0.00122 0.00318 -0.00641 0.02594 0.01200 0.00106 0.00058 0.00049 0.00000 0.00338 0.00338 0.00317 0.00263 0.00252 0.00283 0.00134 H5 0.65483 0.63730 0.27983 1.00000 0.03693 0.15965 0.01370 0.00737 0.00665 0.00000 0.02134 C6 0.52440 0.49430 0.35348 1.00000 0.02662 0.02058 0.02071 -0.00242 0.00810 -0.00450 0.02222 0.01178 0.00110 0.00052 0.00050 0.00000 0.00335 0.00316 0.00319 0.00243 0.00267 0.00255 0.00131 H6A 0.40892 0.43484 0.32568 1.00000 0.02876 0.15063 0.01248 0.00689 0.00618 0.00000 0.01934 H6B 0.67069 0.46713 0.36814 1.00000 0.05318 0.18869 0.01710 0.00839 0.00803 0.00000 0.02752 C7 0.50351 0.51670 0.53849 1.00000 0.01839 0.01608 0.02508 -0.00533 0.00445 -0.00284 0.01970 0.01080 0.00099 0.00050 0.00048 0.00000 0.00282 0.00309 0.00336 0.00245 0.00231 0.00243 0.00126 C8 0.45224 0.56486 0.71663 1.00000 0.04359 0.03136 0.01870 -0.00372 0.00794 0.00350 0.03088 0.01305 0.00121 0.00059 0.00051 0.00000 0.00396 0.00361 0.00327 0.00263 0.00287 0.00297 0.00151 C9 0.68328 0.54612 0.76294 1.00000 0.04934 0.04203 0.02508 0.00113 -0.00509 -0.00113 0.03955 0.01434 0.00137 0.00071 0.00059 0.00000 0.00456 0.00439 0.00368 0.00313 0.00323 0.00352 0.00176 H9A 0.73742 0.47535 0.73583 1.00000 0.05933 0.00000 0.00000 H9B 0.68953 0.54095 0.83824 1.00000 0.05933 0.00000 0.00000 H9C 0.77215 0.60994 0.74466 1.00000 0.05933 0.00000 0.00000 C10 0.30825 0.46215 0.72957 1.00000 0.04725 0.04308 0.03533 0.00789 0.02378 0.00274 0.04040 0.01707 0.00140 0.00071 0.00065 0.00000 0.00440 0.00446 0.00425 0.00341 0.00363 0.00362 0.00185 H10A 0.16909 0.47297 0.68786 1.00000 0.06060 0.00000 0.00000 H10B 0.28602 0.45428 0.80241 1.00000 0.06060 0.00000 0.00000 H10C 0.37729 0.39333 0.70675 1.00000 0.06060 0.00000 0.00000 C11 0.35688 0.67038 0.75908 1.00000 0.08078 0.04280 0.03443 -0.01016 0.02068 0.01592 0.05157 0.01825 0.00174 0.00070 0.00066 0.00000 0.00625 0.00476 0.00441 0.00319 0.00429 0.00399 0.00230 H11A 0.44306 0.73673 0.74441 1.00000 0.07736 0.00000 0.00000 H11B 0.35677 0.66253 0.83390 1.00000 0.07736 0.00000 0.00000 H11C 0.20892 0.68038 0.72649 1.00000 0.07736 0.00000 0.00000 C12 0.54817 0.42475 0.03891 1.00000 0.03959 0.04415 0.02119 0.00229 0.00045 -0.00312 0.03522 0.01398 0.00132 0.00069 0.00058 0.00000 0.00410 0.00404 0.00351 0.00307 0.00295 0.00330 0.00161 H12 0.39557 0.43591 0.01954 1.00000 0.07260 0.22757 0.01881 0.01175 0.00907 0.00000 0.03696 C13 0.67627 0.34973 -0.00640 1.00000 0.04318 0.04931 0.01689 -0.00532 0.00047 -0.00156 0.03669 0.01492 0.00127 0.00074 0.00056 0.00000 0.00428 0.00455 0.00351 0.00317 0.00311 0.00347 0.00168 H13 0.62165 0.31264 -0.05751 1.00000 0.02342 0.15056 0.01201 0.00674 0.00656 0.00000 0.01820 C14 0.88432 0.32906 0.03821 1.00000 0.04311 0.03080 0.02475 -0.00345 0.01069 0.00353 0.03236 0.01352 0.00123 0.00064 0.00052 0.00000 0.00398 0.00374 0.00380 0.00272 0.00308 0.00306 0.00158 C15 0.96416 0.38279 0.12965 1.00000 0.02951 0.03200 0.02397 0.00094 0.00237 -0.00474 0.02855 0.01267 0.00118 0.00060 0.00054 0.00000 0.00356 0.00358 0.00340 0.00268 0.00283 0.00288 0.00140 H15 1.08980 0.36569 0.16094 1.00000 0.02494 0.14206 0.01290 0.00653 0.00590 0.00000 0.01871 C16 0.83246 0.45663 0.17644 1.00000 0.03566 0.03377 0.02207 -0.00103 0.00714 -0.00807 0.03020 0.01353 0.00120 0.00062 0.00055 0.00000 0.00373 0.00375 0.00350 0.00283 0.00285 0.00296 0.00148 H16 0.87693 0.49654 0.23493 1.00000 0.02864 0.15451 0.01238 0.00692 0.00654 0.00000 0.01962 C17 0.62577 0.47845 0.13209 1.00000 0.03201 0.03666 0.02097 0.00340 0.00673 -0.00860 0.02959 0.01288 0.00111 0.00062 0.00052 0.00000 0.00349 0.00358 0.00324 0.00275 0.00279 0.00294 0.00143 Final Structure Factor Calculation for neal054 in P2(1) Total number of l.s. parameters = 265 Maximum vector length = 623 Memory required = 56 / 3231 / 29281 wR2 = 0.087275 before cycle 21 for 3118 data and 0 / 265 parameters GooF = S = 1.077; Restrained GooF = 1.077 for 1 restraints Weight = 1 / [ sigma^2(Fo^2) + ( 0.0522 * P )^2 + 1.09 * P ] where P = ( Max ( Fo^2, 0 ) + 2 * Fc^2 ) / 3 wR2 = 0.087275, GooF = S = 1.07693, Restrained GooF = 1.07674 for all data R1 = 0.032459 for 3072 Fo > 4sig(Fo) and 0.032995 for all 3118 data Flack x = -0.024(9) by classical fit to all intensities -0.024(6) from 1408 selected quotients (Parsons' method) Occupancy sum of asymmetric unit = 24.00 for non-hydrogen and 23.00 for H and D atoms Principal mean square atomic displacements U 0.0637 0.0407 0.0244 I1 0.0518 0.0292 0.0229 O1 0.0361 0.0223 0.0133 O2 0.0319 0.0236 0.0134 O3 0.0429 0.0333 0.0201 O4 0.0379 0.0199 0.0174 N1 0.0242 0.0226 0.0136 N2 0.0657 0.0288 0.0240 C1 0.0355 0.0176 0.0133 C2 0.0261 0.0188 0.0173 C3 0.0381 0.0270 0.0192 C4 0.0367 0.0238 0.0173 C5 0.0314 0.0185 0.0168 C6 0.0281 0.0178 0.0132 C7 0.0446 0.0320 0.0160 C8 0.0540 0.0419 0.0228 C9 0.0615 0.0417 0.0179 C10 0.0874 0.0491 0.0182 C11 0.0465 0.0383 0.0208 C12 0.0502 0.0439 0.0159 C13 0.0451 0.0324 0.0196 C14 0.0359 0.0259 0.0239 C15 0.0431 0.0272 0.0203 C16 0.0434 0.0285 0.0169 C17 0 atoms may be split and 0 atoms NPD Analysis of variance for reflections employed in refinement K = Mean[Fo^2] / Mean[Fc^2] for group Fc/Fc(max) 0.000 0.043 0.067 0.087 0.105 0.126 0.150 0.177 0.222 0.290 1.000 Number in group 317. 307. 319. 314. 304. 316. 306. 314. 310. 311. GooF 1.051 1.105 1.057 1.095 1.099 0.942 0.954 1.213 1.001 1.215 K 1.071 1.020 1.011 1.018 1.012 1.008 1.010 0.985 0.986 1.041 Resolution(A) 0.86 0.89 0.93 0.97 1.02 1.08 1.17 1.28 1.47 1.86 inf Number in group 324. 303. 316. 305. 311. 310. 314. 314. 310. 311. GooF 1.162 1.003 1.056 0.999 0.815 0.847 0.854 0.937 1.162 1.668 K 1.014 1.020 1.026 1.017 1.007 0.993 0.975 0.981 0.995 1.059 R1 0.062 0.043 0.041 0.034 0.028 0.024 0.024 0.023 0.028 0.039 Recommended weighting scheme: WGHT 0.0522 1.0939 Most Disagreeable Reflections (* if suppressed or used for Rfree). Error/esd is calculated as sqrt(wD^2/) where w is given by the weight formula, D = Fo^2-Fc^2 and <> refers to the average over all reflections. h k l Fo^2 Fc^2 Error/esd Fc/Fc(max) Resolution(A) 4 -6 7 537.07 850.45 5.63 0.181 0.98 1 3 3 85.14 40.70 4.70 0.039 2.55 5 -3 7 573.95 843.73 4.39 0.180 0.95 1 1 0 152.23 241.24 4.35 0.096 5.50 0 0 4 14334.49 11053.15 4.21 0.651 3.24 3 -4 7 1865.62 2490.99 4.05 0.309 1.19 0 0 1 902.14 1195.88 4.04 0.214 12.95 1 -3 5 134.58 221.72 3.99 0.092 1.98 0 0 5 4009.10 3150.11 3.97 0.347 2.59 -3 0 1 13.15 1.79 3.93 0.008 2.08 0 -2 7 918.63 709.12 3.76 0.165 1.76 2 -6 8 680.50 905.12 3.72 0.186 1.12 1 1 2 1088.67 794.12 3.71 0.174 3.99 1 -1 2 1243.14 894.26 3.66 0.185 3.99 4 -5 7 261.84 368.08 3.59 0.119 1.02 3 -6 7 721.85 948.48 3.57 0.191 1.09 -4 -11 2 128.08 78.13 3.56 0.055 0.88 -2 -2 4 1078.73 834.92 3.54 0.179 2.21 1 -7 8 835.72 1094.97 3.51 0.205 1.13 4 -3 7 226.31 319.18 3.50 0.111 1.08 2 3 5 102.54 62.66 3.40 0.049 1.70 3 -8 7 439.31 583.04 3.39 0.149 0.98 1 0 1 15562.75 12600.54 3.35 0.695 5.37 3 6 0 73.56 120.76 3.28 0.068 1.42 -2 -2 5 208.10 146.64 3.23 0.075 1.99 6 -3 6 343.05 480.07 3.23 0.136 0.87 7 -2 1 210.08 313.69 3.12 0.110 0.87 0 0 7 4991.46 4151.94 3.10 0.399 1.85 2 -3 5 40.89 72.78 3.10 0.053 1.70 2 -7 8 140.68 199.22 3.10 0.087 1.06 -2 2 2 112.79 163.54 3.10 0.079 2.63 -1 -2 2 12506.07 10217.33 3.08 0.626 3.70 1 0 4 11870.92 9914.39 3.08 0.616 2.74 -2 2 4 1035.71 832.37 3.07 0.179 2.21 -2 -13 1 371.56 260.44 3.07 0.100 0.87 0 4 2 2340.27 2857.95 3.07 0.331 2.68 3 11 1 285.32 194.17 3.06 0.086 0.94 -3 2 9 1006.64 1258.28 3.05 0.220 1.22 1 2 2 18412.44 15093.81 3.04 0.760 3.44 1 -3 3 43.02 71.80 3.02 0.052 2.55 2 -4 0 68.65 103.85 2.99 0.063 2.14 -7 0 5 62.36 33.87 2.98 0.036 0.87 -2 -2 2 431.16 328.00 2.96 0.112 2.63 -7 0 2 78.56 46.69 2.96 0.042 0.89 0 2 7 580.45 456.20 2.95 0.132 1.76 2 2 4 12067.28 10091.73 2.95 0.622 2.00 2 0 0 14511.12 12055.03 2.94 0.680 3.11 5 9 3 63.92 20.91 2.87 0.028 0.87 1 1 4 1349.70 1109.01 2.87 0.206 2.67 -2 6 2 33.13 59.45 2.86 0.048 1.63 Bond lengths and angles I1 - Distance Angles C14 2.1014 (0.0070) I1 O1 - Distance Angles C2 1.2252 (0.0082) O1 O2 - Distance Angles C7 1.3411 (0.0074) C8 1.4814 (0.0080) 120.21 (0.48) O2 C7 O3 - Distance Angles C7 1.2228 (0.0078) O3 O4 - Distance Angles C17 1.3674 (0.0088) C5 1.4246 (0.0081) 118.42 (0.54) O4 C17 N1 - Distance Angles C2 1.3314 (0.0086) C1 1.4515 (0.0092) 122.71 (0.71) H1 0.6892 (0.0853) 121.81 (6.58) 115.17 (6.52) N1 C2 C1 N2 - Distance Angles C7 1.3439 (0.0086) C6 1.4523 (0.0079) 121.90 (0.51) C3 1.4659 (0.0080) 124.22 (0.50) 113.00 (0.50) N2 C7 C6 C1 - Distance Angles N1 1.4515 (0.0092) H1A 0.9800 109.47 H1B 0.9800 109.47 109.47 H1C 0.9800 109.47 109.47 109.47 C1 N1 H1A H1B C2 - Distance Angles O1 1.2252 (0.0082) N1 1.3314 (0.0086) 124.77 (0.69) C3 1.5321 (0.0092) 121.43 (0.62) 113.78 (0.56) C2 O1 N1 C3 - Distance Angles N2 1.4659 (0.0080) C4 1.5289 (0.0098) 102.68 (0.51) C2 1.5321 (0.0092) 111.77 (0.50) 112.28 (0.57) H3 0.9908 (0.0705) 113.63 (3.45) 108.13 (3.46) 108.28 (3.39) C3 N2 C4 C2 C4 - Distance Angles C5 1.5055 (0.0102) C3 1.5289 (0.0098) 104.46 (0.56) H4A 0.8950 (0.0823) 115.00 (4.34) 112.58 (4.34) H4B 0.8912 (0.0832) 105.58 (4.71) 101.11 (4.84) 116.53 (6.73) C4 C5 C3 H4A C5 - Distance Angles O4 1.4246 (0.0081) C4 1.5055 (0.0102) 107.75 (0.57) C6 1.5202 (0.0089) 114.16 (0.54) 103.67 (0.53) H5 1.0001 (0.0876) 108.74 (4.99) 106.85 (4.82) 115.06 (4.95) C5 O4 C4 C6 C6 - Distance Angles N2 1.4523 (0.0079) C5 1.5202 (0.0089) 102.77 (0.50) H6A 1.0402 (0.0825) 108.40 (4.32) 107.60 (4.40) H6B 0.9674 (0.1061) 112.55 (6.22) 107.75 (5.96) 116.73 (7.24) C6 N2 C5 H6A C7 - Distance Angles O3 1.2228 (0.0078) O2 1.3411 (0.0074) 125.50 (0.58) N2 1.3439 (0.0086) 124.14 (0.54) 110.35 (0.51) C7 O3 O2 C8 - Distance Angles O2 1.4814 (0.0080) C11 1.5098 (0.0099) 101.52 (0.56) C9 1.5168 (0.0112) 110.63 (0.57) 111.87 (0.68) C10 1.5282 (0.0110) 109.12 (0.59) 110.27 (0.65) 112.83 (0.66) C8 O2 C11 C9 C9 - Distance Angles C8 1.5168 (0.0112) H9A 0.9800 109.47 H9B 0.9800 109.47 109.47 H9C 0.9800 109.47 109.47 109.47 C9 C8 H9A H9B C10 - Distance Angles C8 1.5282 (0.0110) H10A 0.9800 109.47 H10B 0.9800 109.47 109.47 H10C 0.9800 109.47 109.47 109.47 C10 C8 H10A H10B C11 - Distance Angles C8 1.5098 (0.0098) H11A 0.9800 109.47 H11B 0.9800 109.47 109.47 H11C 0.9800 109.47 109.47 109.47 C11 C8 H11A H11B C12 - Distance Angles C13 1.3712 (0.0118) C17 1.4051 (0.0107) 120.08 (0.74) H12 0.9679 (0.1185) 125.67 (7.43) 113.34 (7.22) C12 C13 C17 C13 - Distance Angles C12 1.3712 (0.0118) C14 1.3843 (0.0110) 120.01 (0.73) H13 0.8358 (0.0831) 118.30 (5.31) 121.40 (5.26) C13 C12 C14 C14 - Distance Angles C13 1.3843 (0.0110) C15 1.3901 (0.0101) 120.49 (0.67) I1 2.1014 (0.0070) 119.00 (0.54) 120.41 (0.55) C14 C13 C15 C15 - Distance Angles C16 1.3865 (0.0107) C14 1.3901 (0.0101) 119.30 (0.71) H15 0.8663 (0.0806) 119.43 (5.07) 120.97 (5.12) C15 C16 C14 C16 - Distance Angles C17 1.3782 (0.0108) C15 1.3865 (0.0107) 120.59 (0.69) H16 0.9112 (0.0851) 115.84 (4.92) 123.47 (4.94) C16 C17 C15 C17 - Distance Angles O4 1.3674 (0.0088) C16 1.3782 (0.0108) 126.42 (0.65) C12 1.4051 (0.0107) 114.08 (0.65) 119.50 (0.69) C17 O4 C16 Selected torsion angles 1.13 ( 1.14) C1 - N1 - C2 - O1 179.61 ( 0.67) C1 - N1 - C2 - C3 175.55 ( 0.59) C7 - N2 - C3 - C4 6.14 ( 0.67) C6 - N2 - C3 - C4 -63.90 ( 0.78) C7 - N2 - C3 - C2 126.69 ( 0.57) C6 - N2 - C3 - C2 -42.99 ( 0.89) O1 - C2 - C3 - N2 138.48 ( 0.60) N1 - C2 - C3 - N2 71.80 ( 0.82) O1 - C2 - C3 - C4 -106.74 ( 0.70) N1 - C2 - C3 - C4 -26.47 ( 0.67) N2 - C3 - C4 - C5 -146.67 ( 0.56) C2 - C3 - C4 - C5 -178.74 ( 0.55) C17 - O4 - C5 - C4 -64.19 ( 0.75) C17 - O4 - C5 - C6 158.21 ( 0.55) C3 - C4 - C5 - O4 36.87 ( 0.69) C3 - C4 - C5 - C6 -153.37 ( 0.57) C7 - N2 - C6 - C5 16.32 ( 0.66) C3 - N2 - C6 - C5 -149.25 ( 0.52) O4 - C5 - C6 - N2 -32.31 ( 0.66) C4 - C5 - C6 - N2 -9.97 ( 0.92) C8 - O2 - C7 - O3 170.13 ( 0.55) C8 - O2 - C7 - N2 -9.12 ( 0.93) C6 - N2 - C7 - O3 -177.62 ( 0.57) C3 - N2 - C7 - O3 170.78 ( 0.53) C6 - N2 - C7 - O2 2.28 ( 0.80) C3 - N2 - C7 - O2 -176.51 ( 0.62) C7 - O2 - C8 - C11 64.61 ( 0.76) C7 - O2 - C8 - C9 -60.10 ( 0.75) C7 - O2 - C8 - C10 -1.71 ( 1.18) C17 - C12 - C13 - C14 0.83 ( 1.18) C12 - C13 - C14 - C15 177.26 ( 0.60) C12 - C13 - C14 - I1 0.62 ( 1.08) C13 - C14 - C15 - C16 -175.76 ( 0.51) I1 - C14 - C15 - C16 -1.19 ( 1.04) C14 - C15 - C16 - C17 -14.59 ( 0.95) C5 - O4 - C17 - C16 165.88 ( 0.60) C5 - O4 - C17 - C12 -179.20 ( 0.62) C15 - C16 - C17 - O4 0.31 ( 1.04) C15 - C16 - C17 - C12 -179.29 ( 0.68) C13 - C12 - C17 - O4 1.15 ( 1.09) C13 - C12 - C17 - C16 FMAP and GRID set by program FMAP 2 1 16 GRID -3.846 -2 -2 3.846 2 2 R1 = 0.028636 for 1652 unique reflections after merging for Fourier Electron density synthesis with coefficients Fo-Fc Highest peak 0.87 at 0.2006 0.2408 0.9582 [ 0.93 A from I1 ] Deepest hole -0.47 at 0.1221 0.2053 0.1077 [ 1.78 A from I1 ] Fourier peaks appended to .res file x y z sof U Peak Distances to nearest atoms (including eq.) Q1 1 1.2006 0.2408 -0.0418 1.00000 0.05 0.87 0.93 I1 2.56 C14 2.68 H12 2.80 H13^a Q2 1 0.9761 0.1452 -0.0070 1.00000 0.05 0.84 1.02 I1 2.33 C14 2.98 H13^a 3.05 C13 Q3 1 0.9929 0.2801 -0.0161 1.00000 0.05 0.73 1.00 I1 1.19 C14 2.16 C13 2.28 C15 Q4 1 1.1399 0.1475 -0.0534 1.00000 0.05 0.58 0.91 I1 2.74 C17 2.78 C16^a 2.95 H16 Q5 1 1.1093 0.2064 0.0370 1.00000 0.05 0.40 0.87 I1 2.02 C14 2.49 H15 2.62 C15 Q6 1 0.5142 0.3896 0.5774 1.00000 0.05 0.36 0.72 O3 1.58 C7 1.95 H3 1.98 H10C Q7 1 0.5758 0.4636 0.5590 1.00000 0.05 0.33 0.45 O3 0.80 C7 1.87 O2 1.95 N2 Q8 1 0.6032 0.3840 0.5456 1.00000 0.05 0.32 0.55 O3 1.68 C7 1.84 H1 1.86 H3 Q9 1 0.4027 0.5158 0.4535 1.00000 0.05 0.32 0.56 N2 1.21 C7 1.61 C6 1.82 C3 Q10 1 0.0331 0.6578 0.4443 1.00000 0.05 0.31 0.57 C2 0.84 O1 1.46 N1 2.05 H1 Q11 1 -0.0025 0.6058 0.4937 1.00000 0.05 0.30 0.75 O1 1.27 C2 2.00 N1 2.18 H1B Q12 1 0.3536 0.5136 0.7216 1.00000 0.05 0.29 0.68 C10 0.87 C8 1.28 H10A 1.37 H10B Q13 1 0.4587 0.6722 0.2838 1.00000 0.05 0.28 0.79 C4 1.03 H4A 1.08 C5 1.30 H5 Q14 1 -0.0330 0.7805 0.5056 1.00000 0.05 0.27 0.68 C1 0.77 N1 1.26 H1 1.34 H1C Q15 1 0.4290 0.5824 0.6437 1.00000 0.05 0.26 0.53 O2 0.97 C8 1.69 C7 1.92 C11 Q16 1 0.2269 0.6553 0.4359 1.00000 0.05 0.25 0.72 C2 0.84 C3 1.54 H3 1.64 O1 Q17 1 0.4518 0.6373 0.7356 1.00000 0.05 0.24 0.80 C11 0.89 C8 1.18 H11A 1.50 H11B Q18 1 0.9910 0.2065 0.0992 1.00000 0.05 0.23 1.74 C14 1.81 I1 2.10 H15 2.12 C15 Q19 1 0.4228 0.6885 0.2268 1.00000 0.05 0.22 0.96 H4A 1.13 C4 1.44 C5 1.65 H5 Q20 1 0.4825 0.6412 0.1798 1.00000 0.05 0.22 1.08 O4 1.37 C5 1.59 H5 1.86 C4 Q21 1 0.1646 0.4590 0.7195 1.00000 0.05 0.21 0.45 H10A 0.89 C10 1.25 H10B 1.56 H10C Q22 1 0.9024 0.4058 0.1643 1.00000 0.05 0.21 0.68 C15 0.77 C16^a 1.27 H15 1.43 H16 Q23 1 0.4799 0.3546 0.4232 1.00000 0.05 0.21 1.60 H6A 1.91 C6 1.97 H6B 2.05 O3 Q24 1 0.6141 0.6962 0.1753 1.00000 0.05 0.21 1.52 H5 1.91 O4 1.93 C5 2.26 H4A Q25 1 0.8010 0.3288 -0.0177 1.00000 0.05 0.21 0.85 C14 0.85 C13 1.20 H13^a 2.14 C12 Q26 1 0.5868 0.4203 0.0221 1.00000 0.05 0.21 0.35 C12 1.09 C13 1.21 H12 1.58 C17 Q27 1 1.0178 0.3745 0.0139 1.00000 0.05 0.20 1.07 C14 1.59 C15 1.92 H15 2.08 I1 Q28 1 0.4307 0.6341 0.6043 1.00000 0.05 0.20 0.49 O2 1.67 C8 1.72 C7 2.16 C11 Q29 1 0.5651 0.4428 0.0973 1.00000 0.05 0.20 0.70 C17 0.79 C12 1.38 H12 1.69 O4 Q30 1 0.3205 0.4559 0.7548 1.00000 0.05 0.20 0.34 C10 0.68 H10B 1.05 H10C 1.23 H10A Shortest distances between peaks (including symmetry equivalents) 6 8 0.73 13 19 0.77 15 28 0.80 12 30 0.84 10 11 0.93 19 20 0.94 7 8 0.97 6 7 0.99 21 30 1.03 26 29 1.04 20 24 1.05 5 18 1.16 1 4 1.16 3 27 1.18 2 5 1.20 10 16 1.23 2 4 1.25 3 5 1.28 1 5 1.30 3 25 1.33 12 21 1.34 15 17 1.35 4 5 1.40 12 15 1.42 13 20 1.43 19 24 1.44 1 3 1.45 25 27 1.47 2 18 1.55 12 17 1.58 2 3 1.59 17 28 1.70 10 14 1.72 8 23 1.72 3 18 1.74 7 9 1.76 11 16 1.79 13 24 1.83 25 26 1.84 1 2 1.89 3 4 1.90 9 16 1.97 9 23 2.01 6 23 2.04 7 15 2.06 5 27 2.07 11 14 2.07 1 27 2.12 12 28 2.18 22 27 2.20 7 23 2.21 22 29 2.23 15 30 2.24 6 9 2.25 8 9 2.25 1 24 2.26 18 27 2.28 7 28 2.31 17 30 2.31 18 25 2.32 4 18 2.39 9 28 2.40 4 24 2.41 1 18 2.41 2 25 2.42 16 28 2.42 14 16 2.45 5 25 2.45 15 21 2.49 6 15 2.51 22 25 2.55 22 26 2.55 18 22 2.58 9 15 2.59 25 29 2.60 13 16 2.60 20 29 2.65 6 12 2.67 23 28 2.69 2 27 2.72 7 12 2.73 17 21 2.75 1 25 2.76 26 27 2.76 6 30 2.84 9 10 2.84 9 11 2.85 3 22 2.89 8 16 2.89 9 13 2.93 8 15 2.93 11 28 2.94 4 27 2.94 6 28 2.95 15 16 2.98 Time profile in seconds ----------------------- 0.07: Read and process instructions 0.00: Fit rigid groups 0.00: Interpret restraints etc. 0.00: Generate connectivity array 0.00: Analyse DFIX and DANG restraints 0.00: Analyse SAME, SADI and NCSY restraints 0.00: Generate CHIV restraints 0.00: Check if bonds in residues restrained 0.00: Generate DELU and RIGU restraints 0.00: Generate SIMU restraints 0.00: Generate ISOR restraints 0.00: Analyse electron density 0.00: Analyse other restraints etc. 0.07: Read intensity data, sort/merge etc. 0.00: Set up constraints 0.01: OSF, H-atoms from difference map 0.34: Set up l.s. refinement 0.00: Generate idealized H-atoms 0.56: Structure factors and derivatives 0.23: Sum l.s. matrices 0.00: Generate and apply antibumping restraints 0.01: Apply other restraints 0.20: Solve l.s. equations 0.00: Generate HTAB table 0.10: Other dependent quantities, CIF, tables 0.00: Analysis of variance 0.02: Merge reflections for Fourier and .fcf 0.00: Fourier summations 0.00: Peaksearch 0.00: Analyse peaklist ** WARNING: These times are only approximate for multiple threads. To get better estimates run with -t1 ** Please cite: G.M. Sheldrick (2015) "Crystal structure refinement with SHELXL", Acta Cryst., C71, 3-8 (Open Access) if SHELXL proves useful. +++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++ + neal054 finished at 12:14:31 Total elapsed time: 1.63 secs + +++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++